Development of a component-resolved approach to enhance diagnostic accuracy

Neuherberg/Munich/Luxembourg, February 2016: Researchers from the ZAUM (Dr. Blank, Prof. Schmidt-Weber) in cooperation with the Luxembourg Institute of Health (Prof. Ollert) and the Clinic of Dermatology and Allergy of the Technical University of Munich developed a component-resolved approach to enhance diagnostic accuracy in patients with mastocytosis and hymenoptera venom allergy.

Dr. Simon Blank (ZAUM, TU and Helmholtz Zentrum Munich), Prof. Dr. Markus Ollert (Luxembourg Institute of Health)


The work by Michel et al., demonstrates that in this high risk patient group the use of molecular components and decreasing the threshold sIgE level to 0.1 kU/L may be needed to avoid otherwise undetectable IgE to hymenoptera venom extracts in about 8% of such patients.  Michel et al., Allergy 71(5): 651-660, 2016



Prof. Dr. rer. nat. Carsten B. Schmidt-Weber
Chair for Molecular Allergology (Klinikum rechts der Isar)
Director of the Institute of Allergy research (IAF; Helmholtz Zentrum München)


Zentrum Allergie und Umwelt (ZAUM) 
Technische Universität und Helmholtz Zentrum München

Biedersteiner Str. 29
80802 München

Phone: +49 89 4140-3451
Fax +49 89 4140-3452

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